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Peptide Antibiotics - Discovery, Modes of Action, and Applications

Edited by Charles J Dutton, Mark A Haxell, Hamish A. I. McArthur and Richard G. Wax 
Marcel Dekker  December 2001  



Hardcover  308 pages, Illustrated  ISBN 9780824702458      £127.00
Peptide Antibiotics discusses these unique compounds and their many and exciting applications, including:
  • the distribution and classification of diverse antimicrobial peptides throughout nature
  • the role in host defense of mucosal surface peptide antibiotics such as defensins and cathepsins
  • the biosynthesis of lanthionine-containing antibiotics including nisin, epidermin, and mersacidin
  • the genetic basis determining the production of bacterial peptide antibiotics
  • the potential commercial use of magainin, nisin, and lacticin peptides as anti-infective agents
  • the use of nisin as a commercial food preservative
With contributions from 19 world-renowned experts in the field, Peptide Antibiotics is an indispensable source of information for pharmaceutical scientists, medicinal and organic chemists and biochemists, microbiologists, infectious disease specialists, molecular biologists, and upper-level undergraduate and graduate students in these disciplines.

Contents

Introduction to the Peptide Antibiotics, Harry W. Taber
Sources of Antimicrobial Peptides
Chemistry and Applications of Synthetic Antimicrobial Peptides, David Andreu and Luis Rivas
Lanthionine-Containing Bacterial Peptides, Ulrike Pag and Hans-Georg Sahl
Unmodified Peptide-Bacteriocins (Class II) Produced by Lactic Acid Bacteria, Ingolf F. Nes, Helge Holo, Gunnar Fimland, Håvard Hildeng Hauge, and Jon Nissen-Meyer
Insect Cationic Antimicrobial Peptides, Charles Hetru, Jules A. Hoffmann, and Robert E. W. Hancock
Mammalian Antimicrobial Peptides, Charles L. Bevins and Gill Diamond
Potential Applications of Peptides
Exploitation of Lantibiotic Peptides for Food and Medical Uses, Máire P. Ryan, Colin Hill, and R. Paul Ross
Amphibian Antimicrobial Peptides, Michael A. Zasloff
Index

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Autumn 2001 : Marcel Dekker : antibiotics : biochemistry : biomedical sciences : chemistry : food safety : microbiology : molecular biology : packaging : pharmaceuticals : protein engineering : proteins

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