Transgenic Microalgae as Green Cell Factories
Edited by León, Rosa; Galván, Aurora; Fernández, Emilio
Microalgae have been largely cultured and commercialized as food and feed additives, and their potential as
a source of high-added value compounds is well known. Yet, in contrast to the large number of genetically
modified bacteria, yeast and even higher plants, only a few species of microalgae have been genetically
transformed with efficiency.
Hardcover 578 pp ISBN 9780387755311
More work is needed to transform new species of microalgae, specially those that have commercial value,
so that it would be possible to increase the productivity of traditional compounds or synthesize novel ones.
Silencing transgenes remains as an important limitation for stable expression of foreign genes. This problem
is not unique to microalgae since it has also been observed in plants, animals and fungi. A better understanding
of the mechanisms that control the regulation of gene expression in eukaryotes is therefore needed.
In this book a group of outstanding researchers working on different areas of microalgae biotechnology offer
a global vision of the genetic manipulation of microalgae and their applications.
Of interest to algologists, biotechnologists, and researchers interested in green cell factories
1. Nuclear transformation of eukaryotic, microalgae: historical overview, achievements and problems ,
Rosa León and Emilio Fernández
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2. Transformation of cyanobacteria, Agustín Vioque
3. Molecular biology and the biotechnological - potential of diatoms, Peter Kroth
4. Tools and techniques for chloroplast - transformation of chlamydomonas, Saul Purton
5. Influence of codon bias on the expression of foreign genes in microalgae, Markus Heitzer, Almut Eckert,
Markus Fuhrmann and Christoph Griesbeck
6. In the grip of algal genomics, Arthur R. Grossman
7. Insertional mutagenesis as a tool to study genes/functions in chlamydomonas, Aurora Galván, David
González-Ballester and Emilio Fernández
8. Optimization of recombinant protein expression in the chloroplasts of green algae , Samuel P.
Fletcher, Machiko Muto and Stephen P. Mayfield
9. Phycoremediation of heavy metals using transgenic microalgae, Sathish Rajamani, Surasak Siripornadulsil,
Vanessa Falcao, Moacir Torres,
10. Hydrogen fuel production by transgenic microalgae, Anastasios Melis, Michael Seibert and Maria L. Ghirardi
11. Microalgal vaccines , Surasak Siripornadulsil, Konrad Dabrowski and Richard Sayre
: genetically modified organisms
: plant science