Eukaryotic Transcription Factors, 5th Edition
David S. Latchman
New coverage in this edition includes:
Softcover 488 pp ISBN 9780123739834
- Potential of transcription factors as therapeutic targets in human disease
- Importance of histone modifications
- Use of genome-based sequence analysis and high-throughput methods
- Applications of the chromatin immunoprecipitation (ChIP) assay
- Transcriptional elongation
- Regulation by post-translational modifications
- Regulatory networks and bioinformatics
Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression.
Transcription factors regulate transcription during development and in disease states. As such,
it is critical for researchers to gain a good understanding of the relationship between the structure
of various families of transcription factors and their function, as well as roles in human disease.
Since publication of the Fourth Edition, there have been major advances, notably in the areas
of chromatin remodeling and genome-scale analyses. This complete update includes all new
coverage of the latest developments, from enabling genomic technologies to studies on the
importance of post-translational modifications beyond phosphorylation events.
Of interest to any researcher or student in the life sciences.
To find similar publications, click on a keyword below:
- DNA sequences, transcription factors and chromatin structure;
- Methods for studying transcription factors;
- RNA polymerases and the basal transcriptional complex;
- Families of DNA binding transcription factors;
- Activation of gene expression by transcription factors;
- Repression of gene expression by transcription factors;
- Regulation of transcription factor synthesis;
- Regulation of transcription factor activity;
- Transcription factors and human disease
: cell biology