Mass Spectrometry Basics

Christopher Herbert and Robert Johnstone 
CRC Press  2002  

Hardback  496 pp  ISBN 9780849313547      £133.00
  • Offers a detailed overview of theory and instrumentation
  • Includes over 300 figures and tables
  • Contains over 40 quick guides that serve as a brief overview of the key information in each chapter
  • Provides a glossary of terms that explains the acronyms used in mass spectrometry

Mass Spectrometry Basics provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. The authors describe processes, applications, and the underlying science in a concise manner supported by figures and graphics to further comprehension. The text provides practical approaches to interpreting mass spectral data and step-by-step guides for identifying chemically relevant compounds. Additionally, the authors have included an extensive reference section and a quick guide to each chapter that offers immediate access to key information.

This unique reference makes some of the esoteric aspects of this important area of analysis more readily comprehensible to those who deal with analytical instruments but who have not been trained in mass spectrometry. It also serves as a refresher for practicing mass spectroscopists by clarifying principles to afford a better appreciation and application of this technology.


  • Chemical Ionisation (CI)
  • Laser Desorption Ionisation (LDI)
  • Electron Ionisation (EI)
  • Fast Atom Bombardment (FAB) and Liquid Phase Secondary Ion Mass Spectrometry (LSIMS) Ionisation
  • Field Ionisation (FI) and Field Desorption (FD)
  • Coronas, Plasmas and Arcs
  • Thermal Ionisation (TI; Surface Emission of Ions)
  • Electrospray Ionisation (ES)
  • Atmospheric Pressure Ionisation (API)
  • Z-Spray Combined Inlet/Ion Source
  • Thermospray and Plasmaspray Interface
  • Particle-Beam Interface
  • Dynamic Fast Atom Bombardment and Liquid (phase) Secondary Ion Mass Spectrometry (FAB/LSIMS) Interface
  • Plasma Torches
  • Sample Inlets for Plasma Torches. Part A: Gases
  • Sample Inlets for Plasma Torches. Part B: Liquid Inlets
  • Sample Inlets for Plasma Torches. Part C: Solid Inlets
  • Lasers and Other Light Sources
  • Nebulisers
  • Hybrid Orthogonal Time-of-Flight (oa-TOF) Instruments
  • Hybrid Magnetic Sector Time-of-Flight (TOF) Instruments
  • Hybrid Hexapole Time-of-Flight (TOF) Instruments
  • Hybrid Quadrupole Time-of-Flight (TOF) Instruments
  • Ion Optics of Magnetic/Electric Sector Mass Spectrometers
  • Quadrupole Ion Optics
  • Time-of-Flight (TOF) Ion Optics
  • Orthogonal Time of Flight (oa-TOF) Ion Optics
  • Point Ion Collectors (Detectors)
  • Array Collectors (Detectors)
  • Comparison of Multipoint Collectors (Detectors) of Ions
  • Time-to-Digital Converters
  • Origin and Uses of Metastable Ions
  • Linked Scanning and Metastable Ions in Quadrupole Mass Spectrometry
  • Linked Scanning and Metastable Ions in Magnetic Sector Mass Spectrometry
  • Gas Chromatography (GC) and Liquid Chromatography (LC)
  • Gas Chromatography / Mass Spectrometry (GC/MS)
  • Liquid Chromatography / Mass Spectrometry (LC/MS)
  • High Resolution Accurate Mass Measurement: Element Compositions
  • Choice of Mass Spectrometer
  • Analysis of Peptides and Proteins by Mass Spectrometry
  • EPA Protocols
  • Computers and Transputers in Mass Spectrometers, Part A
  • Computers and Transputers in Mass Spectrometers, Part B
  • Computers and Transputers in Mass Spectrometers, Part C
  • An Introduction to Biotechnology
  • Isotopes and Mass Spectrometry
  • Use of Isotope Ratios
  • Variations in Isotope Ratios
  • Transmission of Ions through Inhomogeneous RF Fields
  • Appendices
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CRC Press : analytical methods : chemistry : chromatography : mass spectrometry

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