Pharmacodynamic Basis of Herbal Medicine - 2nd edition

Manuchair Ebadi 
CRC Press  June 2006  

Hardback  699pp  ISBN 9780849370502      £118.00
About the second edition

  • Addresses more than 150 single herbs as well as foods, vitamins, antioxidants, algae, and natural anti-inflammatories
  • Discusses herb-drug and food-drug interactions and examines adverse effects on a molecular level
  • Includes more than 200 new figures and diagrams to demonstrate the physiological mechanism of these substances in the body and on disease
  • Includes new data from recent studies and clinical trials

About the first edition

Herbal remedies have become a major factor in American health care. Botanicals like Ginseng, Ma Huang, St. John's Wort, and Valerian are now household words throughout the world. Since many of these natural drugs are sold over the counter, often consumers mistakenly assume that they are completely safe. However, serious adverse effects sometimes occur, especially when taken in conjunction with prescription drugs.

Conversely, pharmacists, pharmacologists, and physicians are more hesitant to accept the beneficial effects of herbal drugs without seeing scientific evidence. The Pharmacodynamic Basis of Herbal Medicine provides this evidence and addresses other important issues in a clear, easy-to-understand manner. It breaks down herbal medications to their molecular level to show how they bring about both their healing benefits and their side effects.

Pharmacodynamic Basis of Herbal Medicine gives you a better understanding of how natural products:

  • Provide a number of extremely useful drugs that are difficult, if not impossible, to produce commercially by synthetic means
  • Supply basic compounds that may be modified slightly to render them more effective or less toxic
  • Are useful as prototypes or models for synthetic drugs possessing physiologic activities similar to the original drug
  • Contain compounds that demonstrate little or no activity themselves but which can be modified by chemical or biological methods to produce potent drugs not easily obtained by other methods

Whether they take herbal medicine for religious, philosophical, or economic reasons, Western believers are just discovering what Eastern civilizations have known for centuries. As the use of herbal remedies grows exponentially, so too does the necessity for information on how these herbs actually work. Author Manuchair Ebadi, winner of the 2004 University of North Dakota Foundation Thomas J. Clifford Faculty Achievement Award for Excellence in Research, builds the scientific bridge between Eastern and Western medicine. For a multitude of popularly used herbs it demonstrates the beneficial effects and adverse side effects of herbal drugs, showing their actions and effects on organ, tissue, cellular, and subcellular levels. By understanding and applying the information in this book, you will be able to provide safer and more effective therapeutic care.


  • The Pharmacokinetic Basis of Therapeutics
  • Pharmacodynamics
  • Adverse Reactions and Drug€Drug Interactions
  • Herb€Drug Interactions
  • Natural Products as a Resource for Established and New Drugs
  • Alternative Therapies
  • Herbal Therapeutics Then and Now
  • Dietary Antioxidants
  • Herbal Drugs and Their High Demand in Treating Diseases
  • Algae
  • Alkaloids
  • Aloe and Colon Function
  • Banisterine, Selegiline, and Parkinson€s Disease
  • Belladonna Alkaloids: Autonomic Drugs
  • Blueberry (Vaccinium)
  • Botulinum Toxin
  • Brussels Sprouts
  • Cannabis
  • Capsicum, Rosemary, and Turmeric
  • Carotenoids
  • Chocolate
  • Cinchona Tree
  • Coca
  • Colchicine and Gout
  • Compositae
  • Curare and Neuromuscular Blockade
  • Daffodil and Alzheimer€s Disease
  • Eggplant
  • Ephedrine (Ma Huang): A Decongestant and Vasopressor
  • Ergot, Its Alkaloids, and Headache
  • Flavonoids
  • Flaxseed
  • Folate in Fruit
  • Food€Drug Interactions
  • Foxglove, Cardiac Glycosides, and Congestive Heart Failure
  • Ginkgo biloba
  • Ginseng and Cholinergic Transmission
  • Green, White, and Black Teas
  • Herbal Plants and Tuberculosis
  • Herbal Products for the Chemotherapy of Human Immunodeficiency Virus Infection
  • Honey: The Nectar of Life
  • Horseradish and Antiplatelet Actions
  • Hypericum (St. John€s Wort) and Depression
  • Ipecac
  • Manuka and Fungal Disease
  • Marine Therapeutics
  • Morphine:Papaver somniferum
  • Oats (Avena sativa L.) and Their Antioxidant Activity
  • Olives and Olive Oil
  • Onion and Garlic
  • Immunoenhancing Actions of Plantain
  • Plants and Diabetes
  • Pomegranate
  • Pycnogenol
  • Pygeum africanum and Permixon for the Treatment of Patients with Benign Prostatic Hyperplasia
  • Reserpine
  • Rhubarb
  • Saffron
  • Salicylate
  • Sex Herbs
  • Sponges and Steroids
  • Taxol (Paclitaxel) and Cancer Chemotherapy
  • Tomatoes
  • Ulcer Therapy with Herbal Medicine
  • Valerian
  • Vitamins and Diet
  • Wheat Germ
  • Wine
  • Yogurt and the Immune System

Specific References
General References

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CRC Press : ayurvedic medicine : biochemistry : botanicals : pharmaceuticals : plant science

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